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The potent signaling polypeptide for healthy and younger-looking skin, biomimetic human type XXI collagen polypeptide

HumaColl™21 transcends collagen from a common protein to a powerful bioactive ingredient for skin care.

The first and only biomimetic human type XXI collagen, HumaColl™21 is expertly biodesigned to mimic the active core of the type XXI protein. HumaColl™21 comprises a high concentration of signaling motifs known to aid in skin vitality.

A powerful and active ingredient for beauty, HumaColl™21 has been shown to stimulate core extracellular matrix (ECM) components, combat signs of aging, and improve the appearance of the complexion. A multifunctional polypeptide, HumaColl™21 is an active ingredient that can be used across the spectrum of beauty, from skincare to scalp care to color cosmetics.

Studies have shown HumaColl™21

  • Reduces the appearance of wrinkles
  • Improves skin firmness and elasticity
  • Stimulates multiple ECM components, including collagen, elastin, and hyaluronic acid
  • Reduces skin redness & boosts brightness
  • Improves skin smoothness and softness

Recommended active use rate: 0.1%-1%

HumaColl™21 is biodesigned to meet today’s most in-demand certifications and strict clean beauty standards. HumaColl™21 is free from soy, gluten, known allergens, phthalates, parabens, triclosan, urea, BHT, and BHA.

Type 21 Collagen

There are 28 types of collagen in the human body. Perhaps you have heard of type I and III but get to know Type 21. Type 21 is a rare collagen type, making up less than 1% of the human body by adulthood. Rare but powerful, Type 21 acts as a signaling molecule boosting extra cellular matrix production including vital elements like collagen, fibronectin, and elastin that contribute to the appearance of healthy and youthful skin.

Formulate with HumaColl™21

  • Skin Care
  • Body Care
  • Scalp Care
  • Grooming
  • After-sun Care

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Replenish Skin with The Elements of Skin®

With age, critical proteins like collagen and elastin dramatically decrease in production causing the fine lines, wrinkles, and loose skin. The Elements of Skin® is a unique collection of biomimetic human proteins created through biodesign and precision fermentation. Offering 100% biological match to the primary amino acid sequence of proteins found in humans.

In vitro studies have shown outstanding performance in elements supporting anti-aging and healthy aging benefits:

  • Fibroblast activity​
  • Boosting endogenous proteins, including elastin and collagen​
  • Boosting endogenous hyaluronic acid ​

HumaColl™21 is our biomimetic type 21 human collagen, use alone or in combination with Elastapure®, our biomimetic human elastin, for the full effect of The Elements of Skin®.


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