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Biomimetic Human Type 21 Collagen
for Improved Complexion & Younger Looking Skin

The Elements of Skin™
CEW Award Logo

HumaColl™21 is the first and only vegan biomimetic human type 21 collagen for topical beauty and personal care applications.

HumaColl™21 is a 100% match to the amino acid sequence of human type 21 collagen. Made possible only though the power of biotechnology, HumaColl™21  lives at the intersection of innovation, sustainability, and efficacy as a novel hero ingredient perfect for next-generation beauty products.

Replenish Skin with The Elements of Skin™

With age, critical proteins like collagen and elastin dramatically decrease in production causing the fine lines, wrinkles, and loose skin. The Elements of Skin™ is a unique collection of biomimetic human proteins created through biodesign and precision fermentation. Offering 100% biological match to the primary amino acid sequence of proteins found in humans.

In vitro studies have shown outstanding performance in elements supporting anti-aging and healthy aging benefits:

✔️ Fibroblast activity​
✔️ Boosting endogenous proteins, including elastin and collagen​
✔️ Boosting endogenous hyaluronic acid ​

HumaColl™21 is our biomimetic type 21 human collagen, use alone or in combination with Elastapure®, our biomimetic human elastin, for the full effect of The Elements of Skin™.

Type 21 Collagen

There are 28 types of collagen in the human body. Perhaps you have heard of type I and III but get to know Type 21. Type 21 is a rare collagen type, making up less than 1% of the human body by adulthood. Rare but powerful, Type 21 acts as a signaling molecule boosting extra cellular matrix production including vital elements like collagen, fibronectin, and elastin that contribute to the appearance of healthy and youthful skin.

Look Good with HumaColl™21


We are continually building out our data package for all our ingredients. Below is a sample of our data package for HumaColl™21. Contact us for the full data package, including our clinical study results! ex vivo and in vivo studies have demonstrated:

Stimulates Collagen Type I

90% increase in Collagen Type I production in the dermis compared to untreated control. Outperformed Retinol in ex vivo skin explant assay.

Boost Hyaluronic Acid

Increases HA expression in the epidermis and dermis compared to untreated control, by 106% and 546% respectively. Outperformed Retinol in ex vivo skin explant assay.

Increase Skin Elasticity​

123% increase in elasticity over baseline in clinical study, cutometer measurement. 100% of participants showed improvement​

Reduces Redness

58% reduction in skin redness over baseline, scored by a blinded clinical grader in a clinical study. 78% of participants showed improvement​

Feel good with HumaColl™21

HumaColl™21 is biodesigned to meet today’s most in-demand certifications and strict clean beauty standards. HumaColl™21 is free from soy, gluten, known allergens, phthalates, parabens, triclosan, urea, BHT, and BHA.

Formulate with HumaColl™21

✔️ Skin Care
✔️ Body Care
✔️ Color Cosmetics
✔️ Grooming

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