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Beyond Peptides: Geltor Introduces Matrikine Technology with HumaColl™21 Select

First Type XXI Collagen-Based Matrikine Complex Unlocks Encrypted Signaling Sequences for Advanced Skin Support – Debuting at in-cosmetics Global April 2026 in Paris.

SAN LEANDRO, CA – March 25, 2026Geltor, the leader in biodesigned proteins for beauty and wellness, today announced the launch of HumaColl™21 Select (H21 Select), the first Type XXI collagen-based matrikine complex for topical beauty applications. An ingredient representing the evolution of peptides, it offers beauty brands a new way to differentiate in a crowded market.

The global peptide skincare market is experiencing rapid expansion, growing at 12.3% annually and projected to reach $6.6 billion by 2033 (Market Growth Reports). In parallel, the biotech-derived active ingredients are among the fastest-growing ingredient segments in beauty, with a 11% CAGR (Global Market Insights) through 2030. H21 Select sits at the intersection of these two high-growth segments. As the first Type XXI collagen-based matrikine complex, it offers brands a scientifically distinct positioning that cannot be replicated through traditional peptide synthesis or sourcing, delivering both functional differentiation and marketing distinction.

What Are Matrikines And Why Do They Matter?

While all matrikines are peptides, not all peptides are matrikines. Matrikines are signaling peptides derived from extracellular matrix (ECM) proteins, unlocking encrypted biological sequences that support skin health and appearance.

Building on Clinical Success

H21 Select builds on the proven performance of HumaColl™21, a hero ingredient launched in 2020 it remains the first and only biomimetic human type XXI collagen polypeptide on the market. Type XXI collagen is a rare FACIT collagen known for its rich signaling function, supporting the multiple components of the extracellular matrix. HumaColl™ 21 has demonstrated clinical benefits, including the appearance of improved firmness, reduced wrinkles, enhanced brightness, smoother texture, and more.

H21 Select takes this further through precision proteolysis—a biomimetic process that concentrates signaling activity into a “signal-ready form” designed to enhance potency and speed action, with recommended use levels from 0.1%-1%.

Initial research shows promising results, with 27% greater collagen type I production and 24% greater hyaluronic acid production in in vitrostudies compared to HumaColl™ 21, the full-length polypeptide. More studies and substantiation are in progress.

“HumaColl™21 proved the power of Type XXI collagen signaling with measurable clinical results,” said Nick Ouzounov, PhD, CTO and Co-Founder of Geltor. “H21 Select unlocks these encrypted sequences in their most bioactive form, representing a fundamental shift from generic peptides to targeted, biomimetic matrikine complexes.”

H21 Select is a colorless, odorless, water-soluble ingredient that can easily be used across applications for skincare, body care, scalp treatments, hybrid-color cosmetics, and more. H21 Selects meets clean beauty standards, is 100% animal-free, certified vegan, Halal, and non-GMO.

Availability

HumaColl™21 Select will debut at in-cosmetics Global (Paris, April 14-16, Booth 2A118) and New York Suppliers’ Day (May 19-20, Booth 2449). Request samples at www.geltor.com/humacoll21select or contact sales@geltor.com.

About Geltor

Geltor, headquartered in San Leandro, CA, is the category leader in biodesigned proteins, creating sustainable, high-performance ingredients for the world’s most innovative beauty, food, and wellness brands. By harnessing the power of precision fermentation, Geltor enables a new era of clean, functional, and scalable proteins that meet the evolving needs of consumers worldwide.

 

 

For press inquiries, contact Linda Ferguson at linda@erinturnermarketing.com