INCI (topical use): sr-Helmeted Guineafowl Peptide-1
PrimaColl® is the first and only Type 21 collagen polypeptide biodesigned for beauty from within, skin, hair, and more.
OVERVIEW
PrimaColl® is an award-winning ingredient and the next generation of collagen science, connecting beauty and wellness in a single solution. It’s the first biotech-derived collagen to receive the FDA’s GRAS “no questions” letter, and the first collagen added to the FDA registry since 1999. Available for ingestible use in the US and topical use worldwide, PrimaColl® is among the most versatile collagen polypeptides on the market.
INGREDIENT SPOTLIGHT
The Era of Longevity · First of its kind
Longevity is about living better for longer. PrimaColl® is the first and only biodesigned collagen polypeptide modeled on Type 21 signaling collagen, offering a unique mechanism of action compared to other collagens on the market. PrimaColl® is clinically proven to deliver skin benefits, including improvements in hydration, firmness, elasticity, and wrinkle depth, when consumed daily for 12 weeks*.
* Contact us for details on the full clinical study
PROVEN PERFORMANCE
The Beauty Case for PrimaColl®
Beyond the longevity story, PrimaColl® is built to perform: it works at a fraction of the dose of traditional collagen, is backed by one of the collagen category’s largest clinical trials, and is already proven in market.
Amongst the most versatile and inclusive collagens on the market for topical and ingestible applications.
PrimaColl® is biodesigned to meet today’s most in-demand certifications for the beauty industry. Free from soy, gluten, known allergens, phthalates, parabens, triclosan, urea, BHT, and BHA.
PrimaColl® also meets strict clean beauty standards, supporting finished products formulated with it toward Kosher, Leaping Bunny®, and EWG Verified™ certification.
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INspiring THE MARKET, a collaboration WITH TOSLA
We partnered with TOSLA, a global leader in liquid nutraceutical innovation, on a visionary collaboration that demonstrates the benefits and use case for PrimaColl®. The Signaling Collagen Shot is the first ready-to-drink liquid supplement built on PrimaColl®, in a Cherry-Raspberry flavor powered by TOSLA’s VELIOUS™ Flavor Technology.
Each 30 mL bottle features 1g of PrimaColl®, showcasing what’s possible when PrimaColl®’s potency meets real-world formulation. The Signaling Collagen shot was designed for beauty brands looking to expand into ingestible applications and wellness brands looking to expand their product portfolios.
BENEFITS · TOPICAL APPLICATIONS
Hair Care
Improves manageability, reduces frizz, and combats humidity.
Skin Care
Designed to support firmer and more resilient skin.
Intimate Care
Helps maintain elasticity, comfort, and a healthy moisture balance.
Oral Care
Supports the look and feel of healthy, comfortable gums.
FORMULATE WITH
Hair Care | Skin & Body Care | Scalp Care | Oral Care | Intimate Care | Color Cosmetics | Beauty From Within
Product-Specific FAQ
Yes. It’s made entirely through fermentation. The technical name reflects the amino acid sequence it mimics, not an animal source.
Yes, with a 1–2.5g daily ingestible serving and a 0.1–3% topical use rate.
PrimaColl®’s FDA GRAS “no questions” response applies to the US. It’s not currently authorized as a food ingredient in the EU or UK, and may need separate authorization in Canada. Topical use is available worldwide.
Available as a powder.
1–2.5g daily for ingestible use, 0.1–3% topical.
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